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Antiepileptic drugs can affect bone mineral density


Many antiepileptic drugs can significantly lower bone mineral densities (BMDs) at fracture-relevant sites in high-risk patients. Advise patients taking these medications to monitor their BMDs and consider use of calcium/vitamin D supplements as appropriate.


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Pack AM. Bone disease in epilepsy. Curr Neurol Neurosci Rep. 2004;4:329–34.