Medication Monitor



Generic Name (Trade Name—Company)
Notes
March 1, 2011

Azilsartan

(Edarbi—Takeda)
Treatment of hypertension

Uses:

Treatment of hypertension

Azilsartan is a once-daily angiotensin II receptor blocker. The drug can be given as monotherapy or in combination with other antihypertensive agents to control blood pressure. According to the approved labeling, azilsartan has had a robust clinical trial program with almost 6,000 patients evaluated for efficacy and more than 4,800 evaluated for safety. When compared with valsartan (Diovan—Novartis) 320 mg/d and olmesartan (Benicar—Daiichi-Sankyo) 40 mg/d, treatment with azilsartan 80 mg/d resulted in superior blood pressure reductions. Diarrhea was the most commonly reported adverse event in placebo-controlled trials.