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Novel drug reverses dabigatran effect within minutes

KEY POINT

In patients taking dabigatran (Pradaxa—Boehringer Ingelheim) who had serious bleeding or required an urgent procedure, administration of idarucizumab completely reversed the anticoagulant effect within minutes, according to interim results from the RE–VERSE AD trial. 

SOURCES

Pollack CV et al. Idarucizumab for dabigatran reversal. N Engl J Med. 2015;[Epub ahead of print].

Bauer KA. Targeted anti-anticoagulants [Editorial]. N Engl J Med. 2015;[Epub ahead of print].