Psychiatry

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Antipsychotics increase mortality risk in those with Parkinson disease

KEY POINT

A new study suggests that patients with idiopathic Parkinson disease (PD) who use antipsychotics have more than twice the risk of death compared with patients not using these agents, with first-generation antipsychotics associated with a higher risk of death than second-generation agents.

SOURCES

Weintraub D et al. Association of antipsychotic use with mortality risk in patients with Parkinson disease. JAMA Neurol. 2016;[Epub ahead of print].

Baron MS. Antipsychotics and increased mortality. JAMA Neurol. 2016;[Epub ahead of print].