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Prolonged-release melatonin effective for sleep disturbances in children with neurodevelopmental disabilities


Use of prolonged-release melatonin for children with autism spectrum disorder and sleep disturbances, with or without attention-deficit/hyperactivity disorder, resulted in a longer sleep duration and shorter sleep latency compared with placebo according to results of a trial published in the Journal of the American Academy of Child and Adolescent Psychiatry.


Gringras P, et al. Efficacy and safety of pediatric prolonged-release melatonin for insomnia in children with autism spectrum disorder. J Am Acad Child Adolesc Psychiatry. 2017;56(11):946–57.