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Psychiatry: Could ultra-low-dose buprenorphine reduce suicidal ideation?


Use of ultra-low doses of sublingual buprenorphine reduced suicidal ideation in severely suicidal patients, according to a small, 4-week study published online in the American Journal of Psychiatry.


Yovell Y et al. Ultra-low-dose buprenorphine as a time-limited treatment for severe suicidal ideation: A randomized controlled trial. Am J Psychiatry. 2015;[Epub ahead of print].

Striebel JM et al. The anti-suicidal potential of buprenorphine: a case report. Int J Psychiatry Med. 2014;47:169–74.

Schatzberg AF. Opioids in psychiatric disorders: back to the future [Editorial]? Am J Psychiatry. 2015;[Epub ahead of print].

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