Medication Monitor



Generic Name (Trade Name—Company)
Notes
May 17, 2011

Ketorolac

(Sprix—Luitpold)
Nasal spray for pain management

Uses:

Short-term management (up to 5 d) of moderate to moderately severe pain that requires analgesia at the opioid level 

This new formulation of ketorolac is rapidly absorbed through the nasal mucosa, achieving peak blood levels as quickly as an I.M. injection of the drug. The recommended dose for patients younger than 65 years of age is one spray in each nostril (total dose 31.5 mg) every 6 to 8 hours, up to a maximum daily dose of 126 mg (four doses). For those who are at least 65 years of age, renally impaired, or who weigh less than 50 kg, the recommended dose is one spray in one nostril (total dose: 15.75 mg) every 6 to 8 hours up to a maximum daily dose of 63 mg (four doses). The spray will be marketed in a bottle containing eight sprays, with each spray containing 15.75 mg of ketorolac. The spray bottle needs to be discarded within 24 hours of taking the first dose, even if active drug remains in the container.